A bomb blast has ripped through a crowded market in southern Pakistan, killing at least 64 people and wounding 180 others.
The blast left many victims buried under rubble. Police said many of those wounded in the explosion in Quetta remain in critical condition.
Senior police officer Wazir Khan Nasir said the bomb, set off in a residential suburb, was detonated by remote control.
Another officer, Samiullah Khan, said police were investigating whether the bomb was planted in a rickshaw parked in the crowded vegetable market.
He said the device was detonated while dozens of women and children were shopping.
Local residents rushed the victims to three different area hospitals.
The attack was the deadliest since bomb blasts in the same city killed 86 people in January and led to protests that eventually toppled the local government.
Shiites, a minority in the Sunni Muslim-dominated country, have been increasingly attacked by militant groups who view them as heretics and non-Muslims.
Most of the Shiites in the area are Hazaras, an ethnic group who migrated from Afghanistan over 100 years ago.
In recent years the Shiites have come under renewed attack, mostly at the hands of Laskher-e-Jhangvi, a Sunni militant group.
"This evil force is operating with the patronage of certain elements in the province," said Qayum Changezi, the chairman of a local Hazara organization.
After days of protests following the January attack, Prime Minister Raja Pervaiz Ashraf flew to the city to meet with protesters and sacked the chief minister and his cabinet.
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