Israeli missiles have struck a military research centre near the capital Damascus, setting off explosions, Syrian state television has said.
The rockets were said to have struck a military research centre in Jamraya on the outskirts of the capital in the early hours of this morning.
The building was the target of an earlier Israeli strike in January.
Israel has declined to comment on the latest attack, but a Western intelligence source said "stores of Fateh-110 missiles that were in transit from Iran to Hizbollah" were the target of the strike.
Video footage uploaded online by activists claims to show a huge ball of fire rising into the night sky.
More of the unverified footage uploaded by activists Meanwhile, hundreds of families are fleeing a Syrian coastal area where activists say government troops have massacred nearly 200, many of whom were women and children.
The opponents of Bashar al Assad's regime say that fighters loyal to the President carried out two massacres last night and on Thursday in a Sunni Muslim area driving by a policy of ethnic cleansing.
Activists posted a video online of the bodies of 10 people it said were killed in Ras al Nabaa, in the city of Banias, in an attack overnight.
Half of them were children.
Activists said that the number of dead could be as high as 60.
It comes just two days after pro-Assad militias are alleged to have killed as many as 100 Sunnis in the nearby village of Baida.
Protests in Banias at the beginning of the uprising in 2011 Amateur video showed a man and at least three children dead inside a room.
A baby had burned legs and a body stained with blood. Next to him was a young girl whose face had been deformed after apparently being hit with sharp metal.
Other footage from activists showed entire families killed in their beds, a dead mother cradling her child in her arms, two toddlers lying next to them.
The videos have not been independently verified.
Syria's crisis, that began in March 2011 with pro-democracy protests and later turned into a civil war that has killed an estimated 70,000 people, has largely broken along sectarian lines.
The Sunni majority forms the backbone of the rebellion, while Mr Assad's minority Alawite sect, an offshoot of Shi'ite Islam, anchors the regime's security services and the military's officer corps.
Syria's crisis has claimed the lives of an estimated 70,000 people Other minorities, such as Christians, largely support Mr Assad or stand on the sidelines, worried that the regime's fall would bring about a more Islamist rule.
It has been estimated as many as 4,000 people are fleeing from the predominantly Sunni southern parts of the Mediterranean city of Banias amid fears of further large-scale killings.
The US has condemned the May 2 attack. State Department spokeswoman Jennifer Psaki said: "We strongly condemn atrocities against the civilian population and reinforce our solidarity with the Syrian people."
Her statement added: "The United States is appalled by horrific reports that more than 100 people were killed May 2 in gruesome attacks on the coastal town of Bayda, Syria.
"Regime and Shabiha forces reportedly destroyed the area with mortar fire then stormed the town and executed entire families, including women and children."
It came as Israeli officials confirmed the country's air force carried out a strike against Syria, saying it targeted a shipment of advanced missiles bound for the Lebanese militant group Hizbollah.
The violence in the coastal region shows the sectarian nature of the two-year conflict that has killed tens of thousands and sent more than a million Syrians as refugees to neighbouring countries.
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